At december 31, 2013, dustin company reported this information on its balance sheet. course hero8/25/2023 ![]() The term "strain" refers to minor morphological differences and grower branding rather than distinct cultivated varieties. ![]() Strains have been selected through informal breeding programs with undisclosed parentage and criteria. Abbreviations DALYs = disability-adjusted life years CBD = Cannabinoid SUDEP = Sudden unexpected death in epilepsy GNP = Gross national Product THC = Tetrahydrocannabinol EEG = Electroencephalogram HIPAA = Health Insurance Portability and Accountability Act of 1996 WHO = World Health Organization PAME = Partners against Mortality in EpilepsyĬannabis is an interesting domesticated crop with a long history of cultivation and use. Hence, people with epilepsy are two to three times more likely to die prematurely than people without the disease which is surely a matter of concern to both the health providers and the patient. Epilepsy-related deaths are a significant public health problem, yet are poorly understood and often overlooked. Several countries (including Canada, Netherlands, and Israel) and 23 of 50 states in the United States had permitted the use of cannabis for medicinal purposes, with or without undergoing a systematic medicines approval process. Besides, in many parts of the world, people with epilepsy and their families suffered a lot from stigma and discrimination therefore, making it a social economic burden for hampering the quality of life of the patient as well as, that of the patient caregivers. According to WHO survey, it was estimated that about 80% of the people suffering from epilepsy resided in low-and middle-income countries in which three fourths of people could not access the treatment due to cost-effective or non-availability of the treatment in comparison to the people who availed the conventional treatment responded to only approximately 70% of the time. 6 million disability-adjusted life years (DALYs) lost. In 2012, epilepsy was responsible for approximately 20. 75%, of the global burden of disease due to premature mortality, lost work productivity, health care needs and unhealthy quality of life. On an average, it had been estimated that approximately, 50 million people worldwide were suffering from epilepsy, which thus made it one of the most common neurological diseases globally. On the other hand, increased resistance to conventional drug therapy is another issue which has made researchers to think for the alternative treatment for the long run. There were many conventional treatments discovered up till date to minimize and alleviate the symptoms produced as a result of epilepsy, yet none among them could provide the long term safety and efficacy of the interventional drug. " Epilepsy " defined as a chronic non-communicable disorder of the brain had shown to affect people of all age groups. The present study focused on the use of medicinal cannabis and its derivatives for the treatment of epileptic seizures in children, as well as, adults. Therefore the intention of this study was to analyze the neuropsychological effects and the impact of CBs on the dynamics of neural circuits, and its potential as the drug of addiction. Exploring the impacts of cannabis on the brain is imperative. People with the cannabis-linked deficiency in executive functions have been found to have trouble learning and applying the skills requisite for fruitful recovery, setting them at amplified risk for deterioration to cannabis use. Numerous factors like age of onset and duration of cannabis use regulate the severity of the difficulties. Cannabis use has been revealed to cause cognitive deficits from basic motor coordination to more complex executive functions, for example, the aptitude to plan, organize, make choices, solve glitches, remember, and control emotions as well as behavior. In fact, owing to this plethora of effects, it’s still cryptic how CBs trigger neuronal circuits. Study over the last several decades suggested cannabinoids (CBs) exert copious oftentimes opposite effects on countless neuronal receptors and processes. ![]() In the brain, most areas prevalently having cannabinoid receptors have been associated with behavioral control and cognitive effects due to cannabinoids. Abstract: Cannabis is a federally controlled substance, it’s very familiar to many but its neurobiological substrates are not well-characterized.
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